منابع مشابه
Pyruvate oxidation system of heart muscle.
The DPNHz formed through Reaction 1 is reoxidized by another molecule of pyruvate, in the presence of lactic dehydrogenase, to yield DPN and lactate. With the catalytic amounts of CoA used there is little or no reaction unless the acetyl group is transferred from CoA to an acceptor such as orthophosphate in the presence of transacetylase, or oxalacetate in the presence of condensing enzyme. As ...
متن کاملDirect spectrophotometric studies of the kinetics of oxidation and reduction of ubiquinone of heart-muscle particles.
Spectrophotometric measurement of extinction changes associated with oxidation and reduction of the respiratory components of Keilin & Hartree heart-muscle particles has led to a clearer understanding of the reaction sequence and mechanism of action of these components (Chance, 1952a). In some cases it has been possible to distinguish between components whose reaction kinetics are either consis...
متن کاملSpectrophotometric observations relating to the oxidation-reduction potential of cytochrome b in non-phosphorylating heart-muscle particles.
The oxidation-reduction potential of cytochrome b of heart muscle was estimated by Ball (1938) to be -40mv at pH 7-4 and 250. Since then it has become increasingly evident from the work of Chance (1952a, b) on the kinetics of the respiratory chain and from measurements by Hill (1954, and personal communication) that the true value of the potential is likely to be considerably more positive. In ...
متن کاملI27. the Oxidation of Pyruvate by Heart Muscle
BRAuN-MENENDEZ et al. [1939], working with heart-lung and isolated heart preparations, have shown that pyruvate can be utilized by the mammalian heart. Minced heart muscle, as will be seen later, oxidizes pyruvate at about the same rate as the intact heart, and it was used in the present work for a study of the mechanism of the oxidation of pyruvate. The object of the investigation was to deter...
متن کاملOxidation-Reduction Potentials
In the first part of the book purely physico-chemical considerations of redox potentials are lucidly and thoroughly dealt with, and in the second part their applications to physiology are systematically developed. To a student of physiology, who is not well versed in the principles of electrochemistry, this book will be of great value as the author initiates the reader first into those parts of...
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ژورنال
عنوان ژورنال: Circulation
سال: 1962
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.26.5.937